redundancy – Communicable Diseases Research

Metacells untangle large and complex single-cell transcriptome networks

Metacells는 크고 복잡한 단일 세포 전사체 네트워크를 풉니다.

Article

Published on 2022-08-132022-09-11
Journal: BMC Bioinformatics
[Category] 유전자 메커니즘,

Exposing and Overcoming Limitations of Clinical Laboratory Tests in COVID-19 by Adding Immunological Parameters; A Retrospective Cohort Analysis and Pilot Study

면역학적 매개변수를 추가하여 COVID-19에서 임상 실험실 테스트의 한계를 노출하고 극복합니다. 후향적 코호트 분석 및 파일럿 연구

Article

Published on 2022-06-292022-09-11
Journal: Frontiers in Immunology
[Category] COVID19(2023년), MERS, SARS, 바이오마커,

[키워드] acute phase acute phase reactants Adding adopted age Alanine alanine aminotransferase Algorithm Analysis aspartate Aspartate aminotransferase association Barcelona best Biomarker C-reactive protein category CCL2 chemokines classical clinical clinical and laboratory variables clinical laboratories clinical laboratory clinical laboratory tests Clinical management clinical parameter Clinical parameters clinical variable clinical variables Cohort collected Comorbidity conducted COVID 19 patient COVID 19 patients COVID-19 COVID-19 pandemic COVID-19 patient CXCL10 cytokine Cytokines exploratory feasible fibrinogen filtration rate First wave flow cytometry fraction glomerular filtration rate IL-1ra IL-6 immune response immunological Immunological test immunological tests IMPROVE independent Inflammation Interpretation Laboratory Laboratory test Laboratory tests limitation lymphocyte neutrophil organ organ damage outcome overcome oxygen oxygen saturation pandemic patients performed phenotype pilot study Predictive predictive power predictive risk-profile. predictor Prognosis redundancy reflected SARS-CoV-2 SARS-COV-2 infection severity statistical statistical analysis survival Test two subgroup two subgroups understanding validation cohort validation cohorts variable
[DOI] 10.3389/fimmu.2022.902837 PMC 바로가기 [Article Type] Article

Model-Driven Impact Quantification of Energy Resource Redundancy and Server Rejuvenation on the Dependability of Medical Sensor Networks in Smart Hospitals

Article

Published on 2022-02-182022-10-29
Journal: Sensors (Basel, Switzerland)
[Category] Coronavirus, COVID19(2023년), MERS, SARS,

SARS-CoV-2-Specific Immune Response and the Pathogenesis of COVID-19

SARS-CoV-2-특이 면역 반응과 COVID-19의 병인

Review

Published on 2022-02-022022-09-10
Journal: International Journal of Molecular Sciences
[Category] COVID19(2023년), MERS, SARS, 변종, 진단,

[키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 acute viral infection adaptive Adaptive immunity angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 Antiviral Autoimmune Autoimmunity blockade causative agent cell receptors cells cellular stress Characteristics complications of COVID-19 coronavirus coronavirus disease COVID-19 Critical Cytokines Engagement expressing Factor focus Immunity immunosuppressive include induce infect infected cell infected cells Infection Inflammation initial initial stages Innate immunity interferons Invasion invasion stage involved main receptor majority mechanism molecular mechanism molecular mechanisms overcome pathogenic pathogenicity pathway Post-COVID-19 syndrome Protein receptor receptors Recognition redundancy research finding research findings respiratory response SARS-CoV-2 severe acute respiratory syndrome Coronavirus Spike protein Stage superantigens systemic inflammation target cell the spike protein tissue variant variants Viral virulence virus
[DOI] 10.3390/ijms23031716 PMC 바로가기 [Article Type] Review

Super interactive promoters provide insight into cell type-specific regulatory networks in blood lineage cell types

슈퍼 대화식 프로모터는 혈액 계통 세포 유형에서 세포 유형-특이 적 조절 네트워크에 대한 통찰력을 제공

Research Article

Published on 2022-01-312022-09-06
Journal: PLoS Genetics
[Category] Communicable Disease,

[키워드] Analysis analysis ATAC-seq binding Blood blood cell Blood cells capture CD4 Cell cell type cell types chromatin compendium complex Critical disrupt driven by enhancer enhancers EPHB3 ETS1 explain Express expression level FIVE Follow-up functional Genetic variant GWAS GWAS variant GWAS variants help hematological hypothese identify implication include independent Interaction interactions interactivity Interpretation Lineage locus lymphocyte Lymphocyte count motifs norm overlap Phenotypes PIR Platelet Platelet count promoter promoters provide redundancy Region regions Regulatory regulatory network regulatory region resource strong interactions traits transcription factor transcriptional transcriptional regulation variant variants
[DOI] 10.1371/journal.pgen.1009984 PMC 바로가기 [Article Type] Research Article

How informative were early SARS-CoV-2 treatment and prevention trials? a longitudinal cohort analysis of trials registered on ClinicalTrials.gov

초기 SARS-COV-2 치료 및 예방 시험은 얼마나 유익 했습니까?ClinicalTrials.gov에 등록 된 시험의 종단 코호트 분석

Research Article

Published on 2022-01-212022-09-10
Journal: PLoS ONE
[Category] SARS, 임상, 치료제,

[키워드] amplified Arm Behavioural intervention behavioural interventions Characteristics Clinical research ClinicalTrials Cohort cohort analysis confidence confidence interval COVID COVID-19 criteria drug Efficacy eligibility criteria eligible evaluated exceptional excluded FDA feasibility food Guidance initiated interval over pandemic phase Phase 2 Prevalence Primary outcome proportion recommendation recruitment redundancy Registered regulated reported Research Result SARS-CoV-2 SARS-CoV-2 pandemic SARS-CoV-2 treatment the SARS-CoV-2 Timeliness Treatment treatment regimen Trial trials U.S. Food and Drug Administration
[DOI] 10.1371/journal.pone.0262114 PMC 바로가기 [Article Type] Research Article

Analysis of the initial lot of the CDC 2019-Novel Coronavirus (2019-nCoV) real-time RT-PCR diagnostic panel

CDC 2019- 노벨 코로나 바이러스 (2019-NCOV) 실시간 RT-PCR 진단 패널의 초기 로트 분석

Research Article

Published on 2021-12-152022-08-13
Journal: PLoS ONE
[Category] Biochemistry, MERS, SARS, 치료기술, 치료법, 치료제,

[키워드] 2019-nCoV 3’ end absence addition age amplification Base pairing caused CDC center conducted Contamination Control coronavirus COVID-19 pandemic diagnostic disease control distribution examined False positive False-positive fluorescent Frequency handling identify improvement Improvements increase initial lab Laboratory loci Mutation Novel coronavirus Nucleocapsid gene occurred Panel prevention primer probe probes problem problems public health Quality assurance Quality control reactivity reagent real-time RT-PCR redundancy reported Research resulting reverse primer RT-PCR SARS-CoV-2 detection sensitivity Viral virus detection
[DOI] 10.1371/journal.pone.0260487 PMC 바로가기 [Article Type] Research Article

Rapid, Affordable, and Scalable SARS-CoV-2 Detection From Saliva

타액에서 빠르고 저렴하며 확장 가능한 SARS-CoV-2 감지

Article

Published on 2021-09-012022-09-11
Journal: Journal of biomolecular techniques : JBT
[Category] SARS, 치료기술,

One swab, two tests: Validation of dual SARS-CoV-2 testing on the Abbott ID NOW™

면봉 1개, 테스트 2개: Abbott ID NOW™에 대한 이중 SARS-CoV-2 테스트 검증

Article

Published on 2021-08-012022-09-11
Journal: Journal of Clinical Virology
[Category] MERS, SARS, 진단, 치료기술, 치료제,

Virtual screening of peptides with high affinity for SARS-CoV-2 main protease

SARS-CoV-2 주요 프로테아제에 대한 높은 친화도를 갖는 펩타이드의 가상 스크리닝

Article

Published on 2021-06-012022-09-11
Journal: Computers in biology and medicine
[Category] SARS, 신약개발, 치료제,